An Empirical Scoring Function for the Transmembrane Helical Protein Assembly
نویسندگان
چکیده
منابع مشابه
Optimizing an Empirical Scoring Function for Transmembrane Protein Structure Determination
W examine the problem of transmembrane protein structure determination. Like many questions that arise in biological research, this problem cannot be addressed generally by traditional laboratory experimentation alone. Instead, an approach that integrates experiment and computation is required. We formulate the transmembrane protein structure determination problem as a bound-constrained optimiz...
متن کاملOptimizing and Empirical Scoring Function for Transmembrane Protein Structure Determination
We examine the problem of transmembrane protein structure determination. Like many other questions that arise in biological research, this problem cannot be addressed by traditional laboratory experimentation alone. An approach that integrates experiment and computation is required. We investigate a procedure which states the transmembrane protein structure determination problem as a bound cons...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2012
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2011.11.2576